Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cell biology

Stretched divisions

This article has been updated

Many organ surfaces are covered by a protective epithelial-cell layer. It emerges that such layers are maintained by cell stretching that triggers cell division mediated by the force-sensitive ion-channel protein Piezo1. See Letter p.118

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Piezo1 maintains a stable, even layer of epithelial cells.

Change history

  • 20 February 2017

    The first sentence of the seventh paragraph should have cited reference 3, not 2.

Notes

  1. See all news & views

References

  1. Gudipaty, S. A. et al. Nature 543, 118–121 (2017).

    Article  ADS  CAS  Google Scholar 

  2. Ingber, D. E. FASEB J. 20, 811–827 (2006).

    Article  CAS  Google Scholar 

  3. Coste, B. et al. Science 330, 55–60 (2010).

    Article  ADS  CAS  Google Scholar 

  4. Eisenhoffer, G. T. et al. Nature 484, 546–549 (2012).

    Article  ADS  CAS  Google Scholar 

  5. Marinari, E. et al. Nature 484, 542–545 (2012).

    Article  ADS  CAS  Google Scholar 

  6. Lewis, A. H. & Grandl, J. eLife 4, e12088 (2015).

    Article  Google Scholar 

  7. Dai, J. & Sheetz, M. P. Cold Spring Harb. Symp. Quant. Biol. 60, 567–571 (1995).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Carl-Philipp Heisenberg.

Related audio

Related links

Related links

Related links in Nature Research

Regenerative biology: Skin, heal thyself

Regenerative biology: Innate immunity repairs gut lining

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Heisenberg, CP. Stretched divisions. Nature 543, 43–44 (2017). https://doi.org/10.1038/nature21502

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature21502

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing