Focus 28 April 2016

Amos B. Smith, III: 50 years of Research and Contributions in total synthesis of complex natural products

This web focus features 22 articles published in the latest Smith special issue on Total Synthesis, Bioorganic and Medicinal Chemistry. These articles, including the 3 editorials and 4 reviews that summarize Prof. Smiths great scientific achievements, are available for free access for a limited period.

Content

Amos B Smith, III: chemist, collaborator and mentor
- John L Wood
Editorial27 Apr 2016 The Journal of Antibiotics
Professor Amos B Smith, III
- Toshiaki Sunazuka
Editorial27 Apr 2016 The Journal of Antibiotics
The first total synthesis and the second- or third-generation approach
- Keiichi Ajito
Editorial27 Apr 2016 The Journal of Antibiotics
Organic synthesis in the Smith Group: a personal selection of a dozen lessons learned at the University of Pennsylvania
- Kevin P C Minbiole
Review Article2 Mar 2016 The Journal of Antibiotics
Strategies for construction of the all-carbon macrocyclic skeleton of the ansamycin antibiotic—kendomycin
- Shu Xu
- Hirokazu Arimoto
Review Article10 Feb 2016 The Journal of Antibiotics
The Petasis-Ferrier rearrangement: developments and applications
- Emily C Minbiole
- Kevin P C Minbiole
Review Article6 Jan 2016 The Journal of Antibiotics
Synthesis of the phorboxazoles—potent, architecturally novel marine natural products
- Zachary Shultz
- James W Leahy
Review Article9 Mar 2016 The Journal of Antibiotics
Total syntheses of codonopsinine and 4-epi-codonopsinine via gold-mediated tandem-catalyzed pyrrole synthesis
- Minami Yamaguchi
- Daichi Itagaki
- Hidetoshi Tokuyama
Original Article17 Feb 2016 The Journal of Antibiotics
Synthesis of the ABCDEF and FGHI ring system of yessotoxin and adriatoxin
- Yuan Zhang
- Jon D Rainier
Original Article9 Mar 2016 The Journal of Antibiotics
Practical synthesis of the C-ring precursor of paclitaxel from 3-methoxytoluene
- Keisuke Fukaya
- Yu Yamaguchi
- Noritaka Chida
Original Article10 Feb 2016 The Journal of Antibiotics
Total synthesis of ent-(+)-cinanthrenol A
- Liangyu Zhu
- Rongbiao Tong
Original Article11 Nov 2015 The Journal of Antibiotics
Synthesis and structure–activity relationship study of FD-891: importance of the side chain and C8–C9 epoxide for cytotoxic activity against cancer cells
- Tomohiro Itagaki
- Ayano Kawamata
- Naoki Kanoh
Original Article27 Jan 2016 The Journal of Antibiotics
Stereoselective access to tubuphenylalanine and tubuvaline: improved Mn-mediated radical additions and assembly of a tubulysin tetrapeptide analog
- Gregory K Friestad
- Koushik Banerjee
- Lei Yao
Original Article17 Feb 2016 The Journal of Antibiotics
Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol
- Tomohiro Asakawa
- Yusuke Kawabe
- Toshiyuki Kan
Original Article24 Feb 2016 The Journal of Antibiotics
Proline-based phosphoramidite reagents for the reductive ligation of S-nitrosothiols
- Chung-Min Park
- Tyler D Biggs
- Ming Xian
Original Article13 Jan 2016 The Journal of Antibiotics
Non-antibiotic 12-membered macrolides: design, synthesis and biological evaluation in a cigarette-smoking model
- Akihiro Sugawara
- Hideaki Shima
- Toshiaki Sunazuka
Original Article30 Sep 2015 The Journal of Antibiotics
The use of fluorescently-tagged apoptolidins in cellular uptake and response studies
- Katherine M Chong
- Nalin Leelatian
- Gary A Sulikowski
Original Article9 Mar 2016 The Journal of Antibiotics
Synthetic studies toward citrinadin A: construction of the pentacyclic core
- Monica E McCallum
- Genessa M Smith
- John L Wood
Original Article9 Mar 2016 The Journal of Antibiotics
The enantioselective synthesis and biological evaluation of chimeric promysalin analogs facilitated by diverted total synthesis
- Kyle W Knouse
- William M Wuest
Note10 Feb 2016 The Journal of Antibiotics
Furan-iminium cation cyclization (FIC) in a total synthesis of manzamine alkaloids
- Kazuyuki Tokumaru
- Toshiyuki Ohfusa
- Atsushi Nishida
Note9 Mar 2016 The Journal of Antibiotics
Natural product-derived quaternary ammonium compounds with potent antimicrobial activity
- Maureen D Joyce
- Megan C Jennings
- Kevin PC Minbiole
Note18 Nov 2015 The Journal of Antibiotics
Anti-obesity activities of the yoshinone A and the related marine γ-pyrone compounds
- Tomoyuki Koyama
- Yoshinori Kawazoe
- Daisuke Uemura
NoteOpen Access2 Mar 2016 The Journal of Antibiotics

Amos B. Smith, III: 50 years of Research and Contributions in total synthesis of complex natural products

Content

Amos B Smith, III: chemist, collaborator and mentor

Professor Amos B Smith, III

The first total synthesis and the second- or third-generation approach

Organic synthesis in the Smith Group: a personal selection of a dozen lessons learned at the University of Pennsylvania

Strategies for construction of the all-carbon macrocyclic skeleton of the ansamycin antibiotic—kendomycin

The Petasis-Ferrier rearrangement: developments and applications

Synthesis of the phorboxazoles—potent, architecturally novel marine natural products

Total syntheses of codonopsinine and 4-epi-codonopsinine via gold-mediated tandem-catalyzed pyrrole synthesis

Synthesis of the ABCDEF and FGHI ring system of yessotoxin and adriatoxin

Practical synthesis of the C-ring precursor of paclitaxel from 3-methoxytoluene

Total synthesis of ent-(+)-cinanthrenol A

Synthesis and structure–activity relationship study of FD-891: importance of the side chain and C8–C9 epoxide for cytotoxic activity against cancer cells

Stereoselective access to tubuphenylalanine and tubuvaline: improved Mn-mediated radical additions and assembly of a tubulysin tetrapeptide analog

Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol

Proline-based phosphoramidite reagents for the reductive ligation of S-nitrosothiols

Non-antibiotic 12-membered macrolides: design, synthesis and biological evaluation in a cigarette-smoking model

The use of fluorescently-tagged apoptolidins in cellular uptake and response studies

Synthetic studies toward citrinadin A: construction of the pentacyclic core

The enantioselective synthesis and biological evaluation of chimeric promysalin analogs facilitated by diverted total synthesis

Furan-iminium cation cyclization (FIC) in a total synthesis of manzamine alkaloids

Natural product-derived quaternary ammonium compounds with potent antimicrobial activity

Anti-obesity activities of the yoshinone A and the related marine γ-pyrone compounds

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