Focus 01 May 2017

Special Issue Dedicated to Satoshi Ōmura: A leader and an inspiration in natural products chemistry, and the Nobel Prize Laureate in Physiology or Medicine 2015

Content

Foreword celebrating the career of Professor Satoshi Ōmura
- Kuniaki Tatsuta
Editorial27 Apr 2017 The Journal of Antibiotics
Achievements of Professor Satoshi Ōmura
- Kazuro Shiomi
Editorial27 Apr 2017 The Journal of Antibiotics
The ups and downs of drug discovery: the early history of Fidaxomicin
- James B McAlpine
Perspective18 Jan 2017 The Journal of Antibiotics
Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations
- Andy Crump
Review Article15 Feb 2017 The Journal of Antibiotics
Genus Kitasatospora, taxonomic features and diversity of secondary metabolites
- Yōko Takahashi
Review Article15 Feb 2017 The Journal of Antibiotics
Endophytic actinomycetes: promising source of novel bioactive compounds
- Atsuko Matsumoto
- Yōko Takahashi
Review Article8 Mar 2017 The Journal of Antibiotics
The antibiotic resistance crisis, with a focus on the United States
- Evan Martens
- Arnold L Demain
Review Article1 Mar 2017 The Journal of Antibiotics
Nature nurtures the design of new semi-synthetic macrolide antibiotics
- Prabhavathi Fernandes
- Evan Martens
- David Pereira
Review ArticleOpen Access30 Nov 2016 The Journal of Antibiotics
The master regulator PhoP coordinates phosphate and nitrogen metabolism, respiration, cell differentiation and antibiotic biosynthesis: comparison in Streptomyces coelicolor and Streptomyces avermitilis
- Juan F Martín
- Antonio Rodríguez-García
- Paloma Liras
Review Article15 Mar 2017 The Journal of Antibiotics
Tyropeptins, proteasome inhibitors produced by Kitasatospora sp. MK993-dF2
- Isao Momose
- Takumi Watanabe
Review Article15 Feb 2017 The Journal of Antibiotics
Message from a long-time friend: congratulations on Emeritus Professor Satoshi Ōmura’s accomplishments
- James B McAlpine
Correspondence27 Apr 2017 The Journal of Antibiotics
Enhanced dereplication of fungal cultures via use of mass defect filtering
- Noemi D Paguigan
- Tamam El-Elimat
- Nicholas H Oberlies
Original ArticleOpen Access11 Jan 2017 The Journal of Antibiotics
Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. I. The taxonomy of the producing strain, and the fermentation, isolation and antibacterial activities
- Atsushi Fukumoto
- Yong-Pil Kim
- Kazuro Shiomi
Original Article15 Mar 2017 The Journal of Antibiotics
Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. II. Structure elucidation
- Atsushi Fukumoto
- Yong-Pil Kim
- Kazuro Shiomi
Original Article15 Mar 2017 The Journal of Antibiotics
Total synthesis of (±)-naphthacemycin A₉, possessing both antibacterial activity against methicillin-resistant Staphylococcus aureus and circumventing effect of β-lactam resistance
- Tomoyasu Hirose
- Yasuhiro Kojima
- Toshiaki Sunazuka
Original Article7 Dec 2016 The Journal of Antibiotics
Kribellosides, novel RNA 5′-triphosphatase inhibitors from the rare actinomycete Kribbella sp. MI481-42F6
- Masayuki Igarashi
- Ryuichi Sawa
- Akio Nomoto
Original Article11 Jan 2017 The Journal of Antibiotics
Isomethoxyneihumicin, a new cytotoxic agent produced by marine Nocardiopsis alba KM6-1
- Takashi Fukuda
- Misaki Takahashi
- Hiroshi Tomoda
Original Article21 Dec 2016 The Journal of Antibiotics
Antarlides F–H, new members of the antarlide family produced by Streptomyces sp. BB47
- Shun Saito
- Takahiro Fujimaki
- Masaya Imoto
Original Article8 Feb 2017 The Journal of Antibiotics
Elmenols C-H, new angucycline derivatives isolated from a culture of Streptomyces sp. IFM 11490
- Yixizhuoma
- Naoki Ishikawa
- Masami Ishibashi
Original Article11 Jan 2017 The Journal of Antibiotics
Simamycin (5′-O-geranyluridine): a new prenylated nucleoside from Streptomyces sp.
- Yasuhiro Igarashi
- Takayuki Kyoso
- Tsutomu Oikawa
Original Article18 Jan 2017 The Journal of Antibiotics
Fradiamine A, a new siderophore from the deep-sea actinomycete Streptomyces fradiae MM456M-mF7
- Yasuhiro Takehana
- Maya Umekita
- Masayuki Igarashi
Original Article1 Mar 2017 The Journal of Antibiotics
Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms
- Ayako Nara
- Takuya Hashimoto
- Haruo Ikeda
Original Article15 Mar 2017 The Journal of Antibiotics
Incubation of 2-methylisoborneol synthase with the intermediate analog 2-methylneryl diphosphate
- Wayne KW Chou
- Colin A Gould
- David E Cane
Original Article1 Mar 2017 The Journal of Antibiotics
Cyclization mechanism of phomopsene synthase: mass spectrometry based analysis of various site-specifically labeled terpenes
- Sandip S Shinde
- Atsushi Minami
- Hideaki Oikawa
Original Article8 Mar 2017 The Journal of Antibiotics
Molecular beacons to identify gifted microbes for genome mining
- Richard H Baltz
Original Article25 Jan 2017 The Journal of Antibiotics
Development of a new air-stable structure-simplified nafuredin-γ analog as a potent and selective nematode complex I inhibitor
- Masaki Ohtawa
- Shiho Arima
- Tohru Nagamitsu
Original Article22 Feb 2017 The Journal of Antibiotics
Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives
- Ko Kumura
- Yoshinari Wakiyama
- Keiichi Ajito
Original Article7 Dec 2016 The Journal of Antibiotics
Lipophilic teicoplanin pseudoaglycon derivatives are active against vancomycin- and teicoplanin-resistant enterococci
- Zsolt Szűcs
- Ilona Bereczki
- Pál Herczegh
Original Article1 Feb 2017 The Journal of Antibiotics
Thiazomycin, nocathiacin and analogs show strong activity against clinical strains of drug-resistant Mycobacterium tuberculosis
- Sheo B Singh
- Libo Xu
- Katherine Young
Original Article18 Jan 2017 The Journal of Antibiotics
The synthesis and evaluation of the antiproliferative activity of deacidified GEX1A analogues
- Takamichi Imaizumi
- Hiroshi Nakagawa
- Hideyuki Onodera
Original Article18 Jan 2017 The Journal of Antibiotics
Ivermectin efficacy against Biomphalaria, intermediate host snail vectors of Schistosomiasis
- Naftale Katz
- Neusa Araújo
- Satoshi Ōmura
Original Article15 Mar 2017 The Journal of Antibiotics
Anti-Mycobacterium activity of microbial peptides in a silkworm infection model with Mycobacterium smegmatis
- Akiho Yagi
- Ryuji Uchida
- Hiroshi Tomoda
Original Article27 Apr 2017 The Journal of Antibiotics
MA026, an anti-hepatitis C virus compound, opens tight junctions of the epithelial cell membrane
- Yusuke Kanda
- Youhei Yamasaki
- Takeo Usui
Original Article18 Jan 2017 The Journal of Antibiotics
γ-Ionylidene-type sesquiterpenoids possessing antimicrobial activity against Porphyromonas gingivalis from Ph ellinus linteus and their absolute structure determination
- Tatsuya Shirahata
- Chieko Ino
- Yoshinori Kobayashi
Note22 Mar 2017 The Journal of Antibiotics
Structure and antibacterial activities of new cyclic peptide antibiotics, pargamicins B, C and D, from Amycolatopsis sp. ML1-hF4
- Hideki Hashizume
- Ryuichi Sawa
- Masayuki Igarashi
Note15 Mar 2017 The Journal of Antibiotics
Trachyspic acid 19-butyl ester, a new inhibitor of Plk1 polo box domain-dependent recognition from uncharacterized fungus RKGS-F2684
- Toshihiko Nogawa
- Noriko Ogita
- Hiroyuki Osada
Note18 Jan 2017 The Journal of Antibiotics
Two new sacrolide-class oxylipins from the edible cyanobacterium Aphanothece sacrum
- Naoya Oku
- Sayaka Hana
- Yasuhiro Igarashi
Note8 Mar 2017 The Journal of Antibiotics
Competition and co-regulation of spirotoamide and tautomycetin biosynthesis in Streptomyces griseochromogenes, and isolation and structural elucidation of spirotoamide C and D
- Dong Yang
- Mostafa E Rateb
- Ben Shen
Note15 Feb 2017 The Journal of Antibiotics
Synergistic antifungal indolecarbazoles from Streptomyces sp. CNS-42 associated with traditional Chinese medicine Alisma orientale
- Mei Liu
- Pei Huang
- Xueting Liu
Note11 Jan 2017 The Journal of Antibiotics
Precursor-directed in situ synthesis of Saccharothriolides G and H by the Actinomycete Saccharothrix sp. A1506
- Shan Lu
- Shinichi Nishimura
- Hideaki Kakeya
Note21 Dec 2016 The Journal of Antibiotics

Special Issue Dedicated to Satoshi Ōmura: A leader and an inspiration in natural products chemistry, and the Nobel Prize Laureate in Physiology or Medicine 2015

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