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The sum of the parts is greater than the whole: current research models for congenital heart disease

Nature Cardiovascular Research volume 2, pages 708–710 (2023)Cite this article

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Several experimental systems have been used over the past five decades to address important questions in cardiac development and congenital heart disease. Here we discuss the strengths and limitations of available models, and how the use of different models synergistically is needed for a deeper understanding of these complex diseases.

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Fig. 1: Current methods to study CHD.

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Authors and Affiliations

  1. Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA

    Tahmina Samad & Sean M. Wu

  2. Department of Pediatrics, Stanford University, Stanford, CA, USA

    Tahmina Samad & Sean M. Wu

  3. Division of Cardiology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA

    Tahmina Samad

  4. Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA

    Sean M. Wu

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  1. Tahmina Samad
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  2. Sean M. Wu
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Correspondence to Sean M. Wu.

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Samad, T., Wu, S.M. The sum of the parts is greater than the whole: current research models for congenital heart disease. Nat Cardiovasc Res 2, 708–710 (2023). https://doi.org/10.1038/s44161-023-00308-9

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