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CARDIOIMMUNOLOGY

Immune riders on the cardiac STORM

Nature Cardiovascular Research volume 1, pages 603–604 (2022)Cite this article

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A mouse model of spontaneous arrhythmia in awake mice enables researchers to study how immune cells contribute to this process. The authors find opposing effects of the immune compartment, with neutrophils favoring arrhythmias by increasing oxidative stress and macrophages protecting against it via their phagocytic activity.

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Fig. 1: Different roles for immune cells in cardiac arrhythmia.

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Authors and Affiliations

  1. Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain

    José Ángel Nicolás-Ávila & Andrés Hidalgo

  2. Vascular Biology and Therapeutics Program and Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA

    Andrés Hidalgo

Authors
  1. José Ángel Nicolás-Ávila
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  2. Andrés Hidalgo
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Correspondence to Andrés Hidalgo.

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Competing interests

A.H. is a paid consultor for Flagship Pioneering for matters partly related to this article.

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Nicolás-Ávila, J.Á., Hidalgo, A. Immune riders on the cardiac STORM. Nat Cardiovasc Res 1, 603–604 (2022). https://doi.org/10.1038/s44161-022-00097-7

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