A recent work introduces a cellular deconvolution method, MeDuSA, of estimating cell-state abundance along a one-dimensional trajectory from bulk RNA-seq data with fine resolution and high accuracy, enabling the characterization of cell-state transition in various biological processes.
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Zhang, Z., Huang, J. Cellular deconvolution with continuous transitions. Nat Comput Sci 3, 582–583 (2023). https://doi.org/10.1038/s43588-023-00489-0
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DOI: https://doi.org/10.1038/s43588-023-00489-0