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Tumour immunology

Inflammation meets translation in AML

Nature Cancer volume 4, pages 3–4 (2023)Cite this article

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Acute myeloid leukemia (AML) is a heterogeneous disease with poor prognosis and treatment options. A new study reveals a unique inflammatory signature in pediatric and adult AML malignant cells that is associated with the infiltration of atypical B cells in the bone marrow microenvironment, which adds an independent layer of prognostic information.

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Fig. 1: Inflammation in AML.

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Authors and Affiliations

  1. Schneider Children’s Medical Center, Petach Tikva, Israel

    Asaf D. Yanir & Shai Izraeli

  2. Felsentein Research Institute, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

    Shai Izraeli

  3. Beckman Research Institute, City of Hope, Duarte, CA, USA

    Shai Izraeli

Authors
  1. Asaf D. Yanir
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  2. Shai Izraeli
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Correspondence to Shai Izraeli.

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The authors declare no competing interests.

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Yanir, A.D., Izraeli, S. Inflammation meets translation in AML. Nat Cancer 4, 3–4 (2023). https://doi.org/10.1038/s43018-022-00499-3

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