Analysis of cells shed from the mouse gut, using bulk and single-cell transcriptomics, as well as single-molecule FISH and intravital imaging, revealed that shed cells are diverse, remain viable for a few hours and upregulate anti-microbial gene expression programs.
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References
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This is a summary of: Halpern, B. K. et al. The cellular states and fates of shed intestinal cells. Nat. Metab. https://doi.org/10.1038/s42255-023-00905-9 (2023).
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Dissecting the cellular states and fates of shed mouse intestinal cells. Nat Metab 5, 1854–1855 (2023). https://doi.org/10.1038/s42255-023-00907-7
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DOI: https://doi.org/10.1038/s42255-023-00907-7
