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FUNCTIONAL GENOMICS

Caught in the genetic network: a novel regulator of lipid metabolism

Nature Metabolism volume 2, pages 483–484 (2020)Cite this article

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Genetic-interaction mapping and co-essentiality analyses in human cells reveal the orphan gene C12orf49 (also known as SPRING1) as a novel regulator of lipid-metabolism homeostasis.

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Fig. 1: The genetic interactions and co-essentiality networks of C12orf49 reflect its role in the SREBP pathway.

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Authors and Affiliations

  1. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

    Enrico Girardi & Giulio Superti-Furga

  2. Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria

    Giulio Superti-Furga

Authors
  1. Enrico Girardi
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  2. Giulio Superti-Furga
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Correspondence to Enrico Girardi or Giulio Superti-Furga.

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The authors declare no competing interests.

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Girardi, E., Superti-Furga, G. Caught in the genetic network: a novel regulator of lipid metabolism. Nat Metab 2, 483–484 (2020). https://doi.org/10.1038/s42255-020-0218-5

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