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BIOCATALYSIS

Copper protein constructs for methane oxidation

High-yield production of a functionally active mimic of particulate methane monooxygenase in Escherichia coli has been presented. Investigation of its catalytic mode clarifies the role of duroquinol in biomimetic methanol production.

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Fig. 1: Catalytic cycle for methane production.

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Correspondence to Sunney I. Chan.

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Chan, S.I., Yu, S.SF. Copper protein constructs for methane oxidation. Nat Catal 2, 286–287 (2019). https://doi.org/10.1038/s41929-019-0268-9

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