Correction to: Scientific Reports https://doi.org/10.1038/s41598-017-05762-7, published online 12 July 2017
This Article contains errors in Figure 1 and Figure 2.
Osthole reverses defective osteogenic ability of P-PDLSCs. (A) ALP staining and ARS staining after 7 days (ALP staining) and 21 days (ARS staining) in H-PDLSCs and P-PDLSCs with different concentrations of Osthole (0 Mol/L, 10−4 Mol/L, 10−5 Mol/L, 10−6 Mol/L, 10−7 Mol/L and 10−8 Mol/L). (B) Quantification of ARS staining for light absorbance at 562 nm. (C) Gene expression of Runx2, ALP and Osterix in H-PDLSCs, P-PDLSCs and P-PDLSCs with 10−7 Mol/L Osthole as assayed by qRT-PCR. (D) Protein expression of Runx2, ALP and Osterix in H-PDLSCs, P-PDLSCs and P-PDLSCs with 10−7 Mol/L Osthole as assayed by Western blot. *P < 0.05, **P < 0.01, ns: P ≧ 0.05, n = 3.
Osthole reverses defective osteogenesis of P-PDLSCs through histone acetylation. (A) ALP staining and ARS staining of H-PDLSCs, P-PDLSCs and P-PDLSCs with 10−7 Mol/L Ostholes in P4 (with stimulation), P6 (without stimulation) and P10 (without stimulation). (B) Quantification of ARS staining for light absorbance at 562 nm. (C) qRT-PCR showed gene expression of fifteen histone acetylases in H-PDLSCs and P-PDLSCs. (D) Protein expression of MOZ, MORF, H3K9ac and H3K14ac in H-PDLSCs and P-PDLSCs as assayed by western blot. (E) qRT-PCR showed gene expression of fifteen histone acetylases in P-PDLSCs and P-PDLSCs with 10−7 Mol/L Osthole measured by qRT-PCR. (F) Protein expression of MOZ, MORF, H3K9ac and H3K14ac in P-PDLSCs with 10−7 Mol/L Osthole treatment on day 0, 3, 5, 7, 10 as assayed by western blot. (G) Level of acetylation of H3K9 and H3K14 in P-PDLSCs with 10−7 Mol/L Osthole treatment on day 0, 3, 5, 7, 10 as assayed by EpiQuik Global Acetyl Histone Quantification Kit. *P < 0.05, **P < 0.01, ***P < 0.001, no mark: P ≧ 0.05, n = 3.
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Sun, J., Dong, Z., Zhang, Y. et al. Author Correction: Osthole improves function of periodontitis periodontal ligament stem cells via epigenetic modification in cell sheets engineering. Sci Rep 12, 9040 (2022). https://doi.org/10.1038/s41598-022-10471-x
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DOI: https://doi.org/10.1038/s41598-022-10471-x
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