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Deep brain stimulation during sleep enhances human brain synchrony and memory

Sleep helps to stabilize long-term memories, possibly through the temporal synchronization of neuronal activity in different brain regions. Intracranial stimulation during sleep using prefrontal electric pulses, precisely timed with slow-wave activities in the medial temporal lobe, enhanced the coupling of neuronal oscillations across regions of the human brain and improved memory performance.

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Fig. 1: Synchronized closed-loop deep brain stimulation during sleep improves memory accuracy.

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This is a summary of: Geva-Sagiv, M. et al. Augmenting hippocampal–prefrontal neuronal synchrony in human sleep enhances memory consolidation. Nat. Neurosci. https://doi.org/10.1038/s41593-023-01324-5 (2021).

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Deep brain stimulation during sleep enhances human brain synchrony and memory. Nat Neurosci 26, 930–931 (2023). https://doi.org/10.1038/s41593-023-01342-3

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