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The evolution of embryo models

Nature Methods volume 20, pages 1844–1848 (2023)Cite this article

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The creation of multiple stem-cell-derived models of mammalian embryogenesis is opening many new doors to study human development and brings a need for scientists to demonstrate responsible dialog over the associated ethical issues.

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Fig. 1: Mouse and human embryogenesis.
Fig. 2: Three dimensional stem-cell-based embryo models in mouse and human.

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Acknowledgements

M.Z.-G.’s work on mouse and human embryo models has been supported by the Wellcome Trust, ERC, Open Atlas and NOMIS Foundations.

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Authors and Affiliations

  1. Division of Biology, California Institute of Technology, Pasadena, CA, USA

    Magdalena Zernicka-Goetz

  2. Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

    Magdalena Zernicka-Goetz

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  1. Magdalena Zernicka-Goetz
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Correspondence to Magdalena Zernicka-Goetz.

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Competing interests

M.Z.-G. is an inventor on patents for stem-cell-derived models of the mouse and of the human embryos.

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Zernicka-Goetz, M. The evolution of embryo models. Nat Methods 20, 1844–1848 (2023). https://doi.org/10.1038/s41592-023-02077-6

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