Correction to: Nature Medicine https://doi.org/10.1038/s41591-024-02839-5, published online 1 March 2024

In the version of the article initially published, the pipeline for the cross-ancestry meta-analysis did not accurately code some SNPs such that they were not combined despite being the same polymorphism. To fix this, we correctly annotated the rsIDs for the summary statistics from each ancestry and meta-analyzed them based on the unique rsID for each polymorphism. We also corrected all downstream analyses that used the cross-ancestry meta-analysis data. Table 1 is a summary of the major changes which have been made to the main text and Fig. 1.

Item

Previous analyses (n)

Current analyses (n)

Autosomal SNPs included in meta-analyses

16,254,110

15,895,579

Genome-wide significant variants

4,416

4,364

Linkage disequilibrium clumped index variants

158

162

Independent loci

126

125

New pain loci

69

66

Exonic variants

5

4

Pleiotropic loci with immune traits

25

23

Gene-set analyses

Catecholamine uptake and startle response

Dopaminergic synaptic transmission and aryl hydrocarbon receptor complex

None of these changes changed any of our downstream analyses. These corrections have been made to the HTML and PDF versions of the article.