Correction to: Nature Medicine https://doi.org/10.1038/s41591-024-02839-5, published online 1 March 2024
In the version of the article initially published, the pipeline for the cross-ancestry meta-analysis did not accurately code some SNPs such that they were not combined despite being the same polymorphism. To fix this, we correctly annotated the rsIDs for the summary statistics from each ancestry and meta-analyzed them based on the unique rsID for each polymorphism. We also corrected all downstream analyses that used the cross-ancestry meta-analysis data. Table 1 is a summary of the major changes which have been made to the main text and Fig. 1.
Item | Previous analyses (n) | Current analyses (n) |
Autosomal SNPs included in meta-analyses | 16,254,110 | 15,895,579 |
Genome-wide significant variants | 4,416 | 4,364 |
Linkage disequilibrium clumped index variants | 158 | 162 |
Independent loci | 126 | 125 |
New pain loci | 69 | 66 |
Exonic variants | 5 | 4 |
Pleiotropic loci with immune traits | 25 | 23 |
Gene-set analyses | Catecholamine uptake and startle response | Dopaminergic synaptic transmission and aryl hydrocarbon receptor complex |
None of these changes changed any of our downstream analyses. These corrections have been made to the HTML and PDF versions of the article.
Author information
Authors and Affiliations
Consortia
Corresponding author
Rights and permissions
About this article
Cite this article
Toikumo, S., Vickers-Smith, R., Jinwala, Z. et al. Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nat Med (2024). https://doi.org/10.1038/s41591-024-03024-4
Published:
DOI: https://doi.org/10.1038/s41591-024-03024-4