Genetics has played a key role in understanding the relationship between the DNA sequence encoding a protein and the protein’s three-dimensional structure. Two new studies present similar analytical approaches to predict three-dimensional structure on the basis of genetic interaction data.
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Chiasson, M., Fowler, D.M. Mutagenesis-based protein structure determination. Nat Genet 51, 1072–1073 (2019). https://doi.org/10.1038/s41588-019-0461-4
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DOI: https://doi.org/10.1038/s41588-019-0461-4