Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Proteomics

A new mass analyzer shakes up the proteomics field

A new mass analyzer enables protein identification at high speed and depth.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: The technology development cycle in proteomics.

References

  1. Guzman, U. H. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-02099-7 (2024).

    Article  Google Scholar 

  2. Hughes, C. S. et al. Nat. Protoc. 14, 68–85 (2019).

    Article  CAS  PubMed  Google Scholar 

  3. Makarov, A. Anal. Chem 72, 1156–1162 (2000).

    Article  CAS  PubMed  Google Scholar 

  4. Meier, F. et al. Mol. Cell. Proteomics 17, 2534–2545 (2018).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Gessulat, S. et al. Nat. Methods 16, 509–518 (2019).

    Article  CAS  PubMed  Google Scholar 

  6. Stewart, H. et al. Anal. Chem. https://doi.org/10.1021/acs.analchem.3c02856 (2023).

  7. Petrosius, V. et al. Preprint at bioRxiv https://doi.org/10.1101/2023.06.06.543943 (2023).

  8. Thielert, M. et al. Mol. Syst. Biol. 19, e11503 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Ivanov, M. V., Garibova, L. A., Postoenko, V. I., Levitsky, L. I. & Gorshkov, M. V. Proteomics 24, 2300090 (2024).

  10. Heil, L. R. et al. Evaluating the performance of the Astral mass analyzer for quantitative proteomics using data independent acquisition. Preprint at bioRxiv https://doi.org/10.1101/2023.06.03.543570 (2023).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Bernhard Kuster.

Ethics declarations

Competing interests

B.K. is a founder and shareholder of OmicScouts and MSAID. He has no operational role in either company. All other authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kuster, B., Tüshaus, J. & Bayer, F.P. A new mass analyzer shakes up the proteomics field. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02129-y

Download citation

  • Published:

  • DOI: https://doi.org/10.1038/s41587-024-02129-y

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing