Timing of dialysis initiation in critically ill patients is controversial. The STARRT-AKI trial reports that an accelerated initiation strategy did not improve 90-day survival and increased dialysis dependency compared with a standard approach in which patients had greater fluid accumulation and metabolic complications at initiation but 38% avoided dialysis.
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Acknowledgements
R.M has received funding from an NIH NIDDK Grant DK079337 for the UAB-UCSD O’Brien center for AKI Research.
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Bouchard, J., Mehta, R. Wait and see approach for dialysis in acute kidney injury. Nat Rev Nephrol 16, 707–708 (2020). https://doi.org/10.1038/s41581-020-00351-w
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DOI: https://doi.org/10.1038/s41581-020-00351-w