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METABOLISM

New insights into energy and protein homeostasis by the kidney

Nature Reviews Nephrology volume 15, pages 596–598 (2019)Cite this article

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Understanding of the cardinal role of the kidneys in maintaining fluid and electrolyte homeostasis is deeply rooted in nephrology. However, the fact that the kidney regulates protein and energy homeostasis similarly to the liver has long been overlooked. Comprehensive whole-body metabolomics studies now shed light on this important aspect of kidney function.

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Fig. 1: The role of the kidney in whole-body homeostasis.

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Authors and Affiliations

  1. Department of Medicine, Leiden University Medical Center, Leiden, Netherlands

    Ton J. Rabelink

  2. Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands

    Martin Giera

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  1. Ton J. Rabelink
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  2. Martin Giera
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Correspondence to Ton J. Rabelink.

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The authors declare no competing interests.

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Rabelink, T.J., Giera, M. New insights into energy and protein homeostasis by the kidney. Nat Rev Nephrol 15, 596–598 (2019). https://doi.org/10.1038/s41581-019-0192-x

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