Genome Watch | Published:

Juggling resistance mutations

Nature Reviews Microbiologyvolume 16page332 (2018) | Download Citation

This month’s Genome Watch discusses how a better understanding of the genetic mechanisms of antimalarial drug resistance can maximize the utility of genomic surveillance programs in informing the most effective drug policy.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    Imwong, M. et al. The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study. Lancet Infect. Dis. 17, 491–497 (2017).

  2. 2.

    Amato, R. et al. Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study. Lancet Infect. Dis. 18, 337–345 (2018).

  3. 3.

    Cowell, A. N. et al. Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics. Science 359, 191–199 (2018).

Download references

Author information


  1. Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK

    • Gavin G. Rutledge
    •  & Roberto Amato


  1. Search for Gavin G. Rutledge in:

  2. Search for Roberto Amato in:

Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Gavin G. Rutledge.

About this article

Publication history



Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing