Genome Watch | Published:

Juggling resistance mutations

Nature Reviews Microbiologyvolume 16page332 (2018) | Download Citation

This month’s Genome Watch discusses how a better understanding of the genetic mechanisms of antimalarial drug resistance can maximize the utility of genomic surveillance programs in informing the most effective drug policy.

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References

  1. 1.

    Imwong, M. et al. The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study. Lancet Infect. Dis. 17, 491–497 (2017).

  2. 2.

    Amato, R. et al. Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study. Lancet Infect. Dis. 18, 337–345 (2018).

  3. 3.

    Cowell, A. N. et al. Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics. Science 359, 191–199 (2018).

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Author information

Affiliations

  1. Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK

    • Gavin G. Rutledge
    •  & Roberto Amato

Authors

  1. Search for Gavin G. Rutledge in:

  2. Search for Roberto Amato in:

Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Gavin G. Rutledge.

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DOI

https://doi.org/10.1038/s41579-018-0008-1

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