A new study provides mechanistic insight into the carcinogenic potential of human colonic mucosal microbial biofilms, confirming that both microbiota composition and organization along with the host inflammatory response are contributing factors to creating the ‘perfect storm’ in terms of colorectal carcinogenesis.
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Hold, G.L., Allen-Vercoe, E. Gut microbial biofilm composition and organisation holds the key to CRC. Nat Rev Gastroenterol Hepatol 16, 329–330 (2019). https://doi.org/10.1038/s41575-019-0148-4
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DOI: https://doi.org/10.1038/s41575-019-0148-4