Excessive salt intake is a known risk factor for cardiovascular disease commonly associated with hypertension. However, we propose that a high-salt diet can promote cardiovascular and other diseases independently of high blood pressure through inflammatory pathways that increase the production of myeloid cells.
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Acknowledgements
M.K.S.L. (2018214) and A.J.M. (1194329) are supported by investigator grants from the National Health and Medical Research Council of Australia.
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World Action on Salt, Sugar and Health: https://www.worldactiononsalt.com/
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Lee, M.K.S., Murphy, A.J. A high-salt diet promotes atherosclerosis by altering haematopoiesis. Nat Rev Cardiol 20, 435–436 (2023). https://doi.org/10.1038/s41569-023-00879-x
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DOI: https://doi.org/10.1038/s41569-023-00879-x
