The antimicrobial agent epifadin, which is produced by the nasal commensal Staphylococcus epidermidis, has— despite its short half-life — broad-spectrum activity, including against Staphylococcus aureus.
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References
Sorbara, M. T. & Pamer, E. G. Nat. Rev. Microbiol. 20, 365–380 (2022).
Gavriilidou, A. et al. Nat. Microbiol. 7, 726–735 (2022).
Torres Salazar, B. O. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-023-01544-2 (2023).
Dougherty, M. W. & Jobin, C. Toxins 13, 346 (2021).
Heilbronner, S., Krismer, B., Brötz-Oesterhelt, H. & Peschel, A. Nat. Rev. Microbiol. 19, 726–739 (2021).
Barbour, A., Wescombe, P. & Smith, L. Trends Microbiol. 28, 578–593 (2020).
Zipperer, A. et al. Nature 535, 511–516 (2016).
Joyner, P. M. et al. Org. Biomol. Chem. 8, 5486–5489 (2010).
Walesch, S. et al. EMBO Rep. 24, e56033 (2023).
Hirsch, P. et al. Nuc. Acids Res. https://doi.org/10.1093/nar/gkad1086 (2023).
Mullowney, M. W. et al. Nat. Rev. Drug Discov. 22, 895–916 (2023).
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R.M. and A.K. are co-founders of MooH GmbH, a company that develops oral metagenomic diagnostics and probiotics.
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Beemelmanns, C., Keller, A. & Müller, R. Mining the microbiota for antibiotics. Nat Microbiol 9, 13–14 (2024). https://doi.org/10.1038/s41564-023-01568-8
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DOI: https://doi.org/10.1038/s41564-023-01568-8
