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Viral pathogenesis

Splenic macrophages escalate dengue disease

Nature Microbiology volume 8, pages 1378–1379 (2023)Cite this article

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A mouse model identifies FcγRIIIa engagement on splenic macrophages as a driver of disease severity during dengue infection.

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Fig. 1: Pro-inflammatory response after FcγRIIIa activation on splenic macrophages.

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Acknowledgements

Our research is supported by the Intramural Research Program of the National Institute of Allergy and Infectious Diseases.

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Authors and Affiliations

  1. Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA

    Megan M. Dunagan & Julie M. Fox

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  1. Megan M. Dunagan
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  2. Julie M. Fox
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Correspondence to Julie M. Fox.

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The authors declare no competing interests.

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Dunagan, M.M., Fox, J.M. Splenic macrophages escalate dengue disease. Nat Microbiol 8, 1378–1379 (2023). https://doi.org/10.1038/s41564-023-01437-4

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