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CELL MIGRATION

In search of a softer environment

By maximizing cell–substrate force transmission, cancer cells can migrate towards either stiffer or softer substrate regions.

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Fig. 1: Mechanisms of durotaxis.
Fig. 2: Moving towards optimal forces.

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Correspondence to Pere Roca-Cusachs.

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Beedle, A.E.M., Roca-Cusachs, P. In search of a softer environment. Nat. Mater. 21, 995–996 (2022). https://doi.org/10.1038/s41563-022-01345-8

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