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Cell invasion

Molecular basis for fluidization of cancer cells

A molecular pathway has been identified in the regulation of unjamming to overcome cancer cell migration and proliferation arrest leading to collective cell invasion.

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Fig. 1: RAB5A promotes collective invasion in tumour spheroids.

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Correspondence to René Marc Mège.

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Mège, R.M. Molecular basis for fluidization of cancer cells. Nat. Mater. 18, 1147–1148 (2019). https://doi.org/10.1038/s41563-019-0521-2

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