With their ability to give rise to many different cell types, stem cells have long been a target of scientists who seek to achieve control over their differentiation. New evidence suggests that stem cells influence their own fates through protein deposition and physical remodelling of their microenvironment.
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Qiao, E.L., Kumar, S. & Schaffer, D.V. Mastering their own fates through the matrix. Nat. Mater. 18, 779–780 (2019). https://doi.org/10.1038/s41563-019-0429-x
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DOI: https://doi.org/10.1038/s41563-019-0429-x
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