Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

IMPLANTED DEVICES

Intravascular stimulation of the motor cortex

Minimally invasive intravascular electrodes chronically implanted via the superior sagittal sinus can stimulate the motor cortex of sheep, and elicit muscular activity.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Intravascular neurostimulation of the motor cortex of sheep.

References

  1. Ben-Menachem, E. et al. Epilepsia 35, 616–626 (1994).

    Article  CAS  Google Scholar 

  2. Morrell, M. J. Neurology 77, 1295–1304 (2011).

    Article  Google Scholar 

  3. Fisher, R. et al. Epilepsia 51, 899–908 (2010).

    Article  Google Scholar 

  4. Boon, P., De Cock, E., Mertens, A. & Trinka, E. Curr. Opin. Neurol. 31, 198–210 (2018).

    PubMed  Google Scholar 

  5. Penn, R. D., Hilal, S. K., Michelsen, W. J., Goldensohn, E. S. & Driller, J. J. Neurosurgery 38, 239–243 (1973).

    Article  CAS  Google Scholar 

  6. Stoeter, P., Dieterle, L., Meyer, A. & Prey, N. Am. J. Neuroradiol. 16, 1214–1217 (1995).

    CAS  PubMed  Google Scholar 

  7. Mikuni, N. et al. Epilepsia 38, 472–482 (1997).

    Article  CAS  Google Scholar 

  8. Kunieda, T. et al. Epilepsia 41, 1411–1419 (2000).

    Article  CAS  Google Scholar 

  9. Opie, N. L. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-018-0321-z (2018).

    Article  Google Scholar 

  10. Uematsu, S. et al. Neurosurgery 31, 59–72 (1992).

    CAS  PubMed  Google Scholar 

  11. Ribeiro, R. C., Abib, S. C., Aguiar, A. S. & Schettini, S. T. Pediatric Blood Cancer 58, 274–277 (2012).

    Article  Google Scholar 

  12. Coplin, W. M. et al. Neurosurgery 41, 101–109 (1997).

    Article  CAS  Google Scholar 

  13. Opie, N. L. et al. IEEE Trans. Biomed. Eng. 64, 928–934 (2017).

    Article  Google Scholar 

  14. Moulds, R. F. General Pharmacol. 14, 47–53 (1983).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Robert S. Fisher.

Ethics declarations

Competing interests

R.S.F. is a consultant for Medtronic.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fisher, R.S. Intravascular stimulation of the motor cortex. Nat Biomed Eng 2, 883–884 (2018). https://doi.org/10.1038/s41551-018-0330-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41551-018-0330-y

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing