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Dissecting the spatial distribution of specialized metabolism at single-cell resolution

The higher-order organization of the monoterpenoid indole alkaloid biosynthesis in Catharanthus roseus leaves was dissected using single-cell RNA sequencing. This work opens the door to elucidate the spatial distribution of plant specialized metabolism at single-cell resolution, which will improve our understanding of the biosynthesis, transport and storage of specialized metabolites.

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Fig. 1: The spatial organization of monoterpenoid indole alkaloid (MIA) metabolism in Catharanthus roseus leaves.

References

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This is a summary of: Sun, S. et al. Single-cell RNA sequencing provides a high-resolution roadmap for understanding the multicellular compartmentation of specialized metabolism. Nat. Plants https://doi.org/10.1038/s41477-022-01291-y (2022).

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Dissecting the spatial distribution of specialized metabolism at single-cell resolution. Nat. Plants 9, 11–12 (2023). https://doi.org/10.1038/s41477-022-01292-x

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