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Nutritional risk assessment at admission can predict subsequent muscle loss in critically ill patients

European Journal of Clinical Nutrition volume 72, pages 1187–1190 (2018)Cite this article

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Abstract

Muscle loss in critically ill patients may be related to nutrition. We study the association between modified NUTrition RIsk in the Critically ill (mNUTRIC) score obtained at admission to intensive care unit (ICU) and subsequent muscle loss. We measured rectus femoris cross-sectional area (RFCSA) by ultrasound on days 1, 3, 7, and 10 of ICU admission. We used linear mixed effects model following natural logarithmic transformation of the data. Forty-eight patients (median (IQR) age 66 (55–72.5) years, 71% male, APACHE II score 31 (25–34), BMI 24.2 (21.5–27.1) kg/m2) were analyzed. The high mNUTRIC score (>5) cohort (n = 35) lost significantly more muscle as compared to the low (≤5) group (n = 13); the adjusted ratio (high versus low group) of the geometric mean RFCSA were (0.58, 95% CI 0.46–0.75) for right and (0.61, 95% CI 0.49–0.77) for left, both p < 0.001. mNUTRIC score obtained at admission to ICU can identify patients at risk of subsequent muscle loss.

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Funding

The study was supported with National University Health System Clinician Grant 2013.

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Authors and Affiliations

  1. Division of Respiratory and Critical Care Medicine, University Medicine Cluster, National University Health System and National University of Singapore, Singapore, Singapore

    Amartya Mukhopadhyay, Deepa Remani & Zudin Amika Puthucheary

  2. Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore

    Bee Choo Tai

  3. Clinical Nutrition Research Centre, Singapore Institute for Clinical Sciences, Singapore, Singapore

    Jeya Henry

  4. Alice Lee Centre for Nursing Studies, National University of Singapore and National University Health System, Singapore, Singapore

    Yanika Kowitlawakul

  5. Intensive Care Department, Royal Free Hospital NHS Trust, Hampstead, United Kingdom

    Zudin Amika Puthucheary

Authors
  1. Amartya Mukhopadhyay
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  2. Bee Choo Tai
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  3. Deepa Remani
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  5. Yanika Kowitlawakul
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  6. Zudin Amika Puthucheary
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Correspondence to Amartya Mukhopadhyay.

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Mukhopadhyay, A., Tai, B.C., Remani, D. et al. Nutritional risk assessment at admission can predict subsequent muscle loss in critically ill patients. Eur J Clin Nutr 72, 1187–1190 (2018). https://doi.org/10.1038/s41430-018-0144-8

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  • DOI: https://doi.org/10.1038/s41430-018-0144-8

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