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Boosting sericin extraction through alternative silk sources

Polymer Journal volume 53, pages 1425–1437 (2021)Cite this article

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Abstract

Silk sericin (SS) is a natural polymer widely studied in the design of biodegradable materials for cosmetic, biomedical, food, and chemical applications. This work was designed to explore the molecular and structural characteristics of SS extracted from different silk sources with different processing degrees: high-quality cocoons (NCs), defective cocoons (DCs), and raw silk yarn (Y). The last two sources have been less studied. SS solutions were obtained from each source using the high-temperature and high-pressure degumming method (HTHP). The molecular weight distribution and amino acid composition of SS extracts were determined using gel permeation chromatography (GPC) and reversed-phase chromatography (RP HPLC), respectively. SS films were formed from each solution and then characterized by attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), nuclear magnetic resonance spectroscopy (NMR), and differential scanning calorimetry (DSC). Water uptake and degradation of SS films were also evaluated. The molecular characteristics of SS extracts were related to the processing degree of the silk source. Moreover, the properties of SS films seemed to be dominated by the primary structure and the presence of natural impurities in each extract. The results suggest that silk sources could be selected ad hoc to design SS materials with distinctive properties for specific applications.

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Acknowledgements

The authors would like to acknowledge the Organizzazione Internazionale Italo-Latino Americana (IILA) and the Directorate General for Development Cooperation of the Italian Ministry of Foreign Affairs (DGCS/MAE) for their financial support through the Scholarship program for Latin American citizens. The authors also express special thanks to Professor AM and all BIOtech Research Center members for receiving NJ-Q as a visiting Ph.D. researcher. The Colombian Ministry of Science, Technology, and Innovation (MINCIENCIAS) is also recognized for its financial support through project No. 121084468254 and the Ph.D. Grant 785 of 2017.

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Authors and Affiliations

  1. School of Engineering, Universidad Pontificia Bolivariana, Medellín, Colombia

    Natalia Jaramillo-Quiceno & Catalina Álvarez-López

  2. Department of Industrial Engineering and “Klaus Mueller” Magnetic Resonance Laboratory, University of Trento, Trento, Italy

    Emanuela Callone & Sandra Dirè

  3. Department of Industrial Engineering and BIOtech Research Center, University of Trento, Mattarello, Italy

    Antonella Motta

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S.D., C.A.L. and A.M. conceived and supervised the experiments. N.J.Q. and E.C. conceived and performed the experiments. All authors discussed the results and wrote the manuscript.

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Jaramillo-Quiceno, N., Callone, E., Dirè, S. et al. Boosting sericin extraction through alternative silk sources. Polym J 53, 1425–1437 (2021). https://doi.org/10.1038/s41428-021-00539-2

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