Retraction to: Cell Death and Disease https://doi.org/10.1038/s41419-018-1002-2, published online 11 September 2018
The Editor-in-Chief has retracted this article. An investigation by the Office of the Vice Chancellor for Research at Washington University in St. Louis concluded that:
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Figure panels 1A, B, and C, labeled as cell line MDA-MB-468, appeared to be falsified and/or fabricated, and were also used in multiple NIH grant applications labeled as breast cancer cell line 4T1 or brain cancer cell line U118.
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Photos in figure panels 2A and 2C, labeled as breast cancer cell line MDA-MB-468, appeared to be falsified, and were also used in multiple NIH grant applications labeled as cell lines 4T1 or BT20.
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Figure panel 2B, labeled as breast cancer cell line MDA-MB-468, appeared to be falsified and/or fabricated, and was also labeled as brain cancer cell line GBM U118 in another publication by the same authors [1].
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Figure 4C, labeled as iFLs from breast cancer cell line MDA-MB-468 in the publication, appeared to be falsified and/or fabricated, and was also used in [1] labeled as iN cells.
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An additional concern identified as part of the investigation is the extensive overlap between this study and another article by the same authors [1].
The authors have not responded to any correspondence from the editor or publisher about this retraction.
Reference
Yuan J, Zhang F, Hallahan D, Zhang Z, He L, Wu L-W, et al. Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors. J Exp Clin Cancer Res. 2018;37:181. https://doi.org/10.1186/s13046-018-0857-5.
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Yuan, J., Zhang, F., You, M. et al. Retraction Note: Identification of protein kinase inhibitors to reprogram breast cancer cells. Cell Death Dis 13, 853 (2022). https://doi.org/10.1038/s41419-022-05311-9
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DOI: https://doi.org/10.1038/s41419-022-05311-9
