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Comparison of senhance and da vinci robotic radical prostatectomy: short-term outcomes, learning curve, and cost analysis

Abstract

Background

The Senhance® Robotic System is a new laparoscopy-based platform that has been increasingly used in radical prostatectomy (RP) procedures. The purpose of this study is to compare the outcome of Senhance RP (SRP) with da Vinci RP (DRP) cases.

Methods

From August 2019 to April 2022, we prospectively recruited 63 cases of SRP. We compared the perioperative data, postoperative complication rates, short-term surgical outcomes (3-month postoperative undetectable prostate-specific antigen (PSA) and incontinence rates), learning curves, and cost analysis with data from 63 matched da Vinci Xi RP cases.

Results

There was no difference in BL (180 versus 180 ml, p = 0.86) and postoperative surgical complication rate (Clavient -Dindo grade I-IV, 25.3 versus 22.2%, p = 0.21) between the SRP cases and the DRP. Regarding the oncologic and continence function, there was no difference between positive margin rate (36.5% versus 41.3%, p = 0.58), rate of undetectable PSA level at postoperative 3 months (68.3 versus 66.7%, p = 0.85), and incontinence rate (14.3 versus 15.9%, p = 1.0) at postoperative 3 months between the two cohorts. The learning curve showed a quick downward slope for laparoscopic experienced surgeons. The median pocket cost for SRP patients in our hospital was $4170, which was lower than $7675 for the DRP patients.

Conclusions

Safety and short-term outcomes are comparable between SRP and DRP. For experienced LRP surgeons, using the Senhance system to perform RP is straightforward. With a more affordable price as its biggest advantage, the Senhance system may serve as a safe and effective alternative for robotic RP.

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Fig. 1: Ports placement and set-up for Senhance robotic radical prostatectomy.
Fig. 2: Operative time (OT) during successive cases for Senhance and da Vinci robotic radical prostatectomy.

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Data availability

The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Authors and Affiliations

Authors

Contributions

Concept: LHY, YCL; Provision of study material or patients: LHY, CYH, YWH, SWH; data acquisition: YCL, LHY; Data analysis and interpretation: YCL, LHY, SWH; manuscript drafting: YCL, LHY; Final approval of manuscript; SWH, CYH, CST; Language editing: TYH. All authors reviewed the paper and agreed to the published version of the manuscript

Corresponding author

Correspondence to Shi-Wei Huang.

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The authors declare no competing interests.

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The study was approved by the Institutional Review Board of National Taiwan University Hospital (Approval code: 202004072RINA).

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Lin, YC., Yuan, LH., Tseng, CS. et al. Comparison of senhance and da vinci robotic radical prostatectomy: short-term outcomes, learning curve, and cost analysis. Prostate Cancer Prostatic Dis 27, 116–121 (2024). https://doi.org/10.1038/s41391-023-00717-8

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