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Reply to 'Non-surgically related causes of erectile dysfunction after bilateral nerve-sparing radical prostatectomy'

Prostate Cancer and Prostatic Diseases volume 20, page 249 (2017)Cite this article

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We read with interest the study of Gandaglia et al., 1 analysing the influence of non-surgically related causes of erectile dysfunction (ED) in patients treated with bilateral nerve-sparing radical prostatectomy (BNSRP). The authors retrospectively evaluated the records of 716 patients with clinically localized prostate cancer (PCa) treated with BNSRP and demonstrated that preoperative functional status and depression should be considered when counseling PCa patients regarding the long-term side effects of BNSRP. However, we would like to discuss several concerns.

The researchers reported that; after 4 years of follow-up, recovery of ED following the surgery is associated with the preoperative functional status, age at surgery, depressive status and adjuvant radiotherapy.

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References

  1. Gandaglia G, Lista G, Fossati N, Suardi N, Gallina A, Moschini M et al. Non-surgically related causes of erectile dysfunction after bilateral nerve-sparing radical prostatectomy. Prostate Cancer Prostatic Dis 2016; 19: 185–190.

    Article  CAS  PubMed  Google Scholar 

  2. Walz J, Gallina A, Saad F, Montorsi F, Perrotte P, Shariat SF et al. A nomogram predicting 10-year life expectancy in candidates for radical prostatectomy or radiotherapy for prostate cancer. J Clin Oncol 2007; 25: 3576–3581.

    Article  PubMed  Google Scholar 

  3. Salinas CA, Tsodikov A, Ishak-Howard M, Cooney KA . Prostate cancer in young men: an important clinical entity. Nat Rev Urol 2014; 11: 317–323.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Resnick MJ, Koyama T, Fan KH, Albertsen PC, Goodman M, Hamilton AS et al. Long-term functional outcomes after treatment for localized prostate cancer. N Engl J Med 2013; 368: 436–445.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Kundu SD, Roehl KA, Eggener SE, Antenor JA, Han M, Catalona WJ . Potency, continence and complications in 3,477 consecutive radical retropubic prostatectomies. J Urol 2004; 172 (6 Pt 1): 2227–2231.

    Article  PubMed  Google Scholar 

  6. Mulhall JP . Defining and reporting erectile function outcomes after radical prostatectomy: challenges and misconceptions. J Urol 2009; 181: 462–471.

    Article  PubMed  Google Scholar 

  7. Walsh PC, Donker PJ . Impotence following radical prostatectomy: insight into etiology and prevention. J Urol 1982; 128: 492–497.

    Article  CAS  PubMed  Google Scholar 

  8. Alba FM, Wang R . Can erectile function be predicted after prostate cancer treatment? Asian J Androl 2012; 14: 134–135.

    Article  PubMed  Google Scholar 

  9. Lee RK, Chughtai B, Te AE, Kaplan SA . Sexual function in men with metabolic syndrome. Urol Clin North Am 2012; 39: 53–62.

    Article  PubMed  Google Scholar 

  10. Rosen RC, Catania J, Pollack L, Althof S, O'Leary M, Seftel AD . Male Sexual Health Questionnaire (MSHQ): scale development and psychometric validation. Urology 2004; 64: 777–782.

    Article  PubMed  Google Scholar 

  11. Fujita K, Landis P, McNeil BK, Pavlovich CP . Serial prostate biopsies are associated with an increased risk of erectile dysfunction in men with prostate cancer on active surveillance. J Urol 2009; 182: 2664–2669.

    Article  PubMed  Google Scholar 

  12. Saitz TR, Serefoglu EC, Trost LW, Thomas R, Hellstrom WJ . The pre-treatment prevalence and types of sexual dysfunction among patients diagnosed with prostate cancer. Andrology 2013; 1: 859–863.

    Article  CAS  PubMed  Google Scholar 

  13. Tuncel A, Kirilmaz U, Nalcacioglu V, Aslan Y, Polat F, Atan A . The impact of transrectal prostate needle biopsy on sexuality in men and their female partners. Urology 2008; 71: 1128–1131.

    Article  PubMed  Google Scholar 

  14. Akbal C, Turker P, Tavukcu HH, Simsek F, Turkeri L . Erectile function in prostate cancer-free patients who underwent prostate saturation biopsy. Eur Urol 2008; 53: 540–544.

    Article  PubMed  Google Scholar 

  15. Klein T, Palisaar RJ, Holz A, Brock M, Noldus J, Hinkel A . The impact of prostate biopsy and periprostatic nerve block on erectile and voiding function: a prospective study. J Urol 2010; 184: 1447–1452.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Urology, Istanbul Training and Research Hospital, Istanbul, Turkey

    M G Culha

  2. Department of Urology, Bagcilar Training and Research Hospital, Istanbul, Turkey

    O O Cakir

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  1. M G Culha
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  2. O O Cakir
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Correspondence to M G Culha.

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Culha, M., Cakir, O. Reply to 'Non-surgically related causes of erectile dysfunction after bilateral nerve-sparing radical prostatectomy'. Prostate Cancer Prostatic Dis 20, 249 (2017). https://doi.org/10.1038/pcan.2017.17

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