In 2011, the US Preventive Service Task Force (USPSTF) recommended that serum PSA-based measurements should not be used to screen men for the presence of prostate cancer. Now, research shows that, following this recommendation, a 28% decline in incident diagnosis of prostate cancer has occurred. Despite this decrease, however, new diagnoses of non-localized prostate cancer have remained unchanged. Only time will tell if this decision has indeed prevented the overdiagnosis of prostate cancer.