Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Prostate cancer

New treatments for localized tumours—what matters first?

High-intensity focused ultrasound (HIFU) represents a fairly new treatment option for focal therapy of prostate cancer. However, studies evaluating its efficacy have not provided strong data to support the use of HIFU in the majority of patients. Thus, high-profile studies investigating feasibility of the modality in terms of adverse effects seem premature.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Ahmed, H. U. et al. Focal therapy for localised unifocal and multifocal prostate cancer: a prospective development study. Lancet Oncol. 13, 622–632 (2012).

    Article  Google Scholar 

  2. Ahmed, H. U. et al. Focal therapy for localized prostate cancer: a phase I/II trial. J. Urol. 185, 1246–1255 (2011).

    Article  CAS  Google Scholar 

  3. Boutier, R. et al. Location of residual cancer after transrectal high-intensity focused ultrasound ablation for clinically localized prostate cancer. BJU Int. 108, 1776–1781 (2011).

    Article  Google Scholar 

  4. Blana, A. et al. Complete high-intensity focused ultrasound in prostate cancer: outcome from the @-Registry. Prostate Cancer Prostatic Dis. doi:10.1038/pcan.2012.10.

  5. Sung, H. H. et al. Seven years of experience with high-intensity focused ultrasound for prostate cancer: advantages and limitations. Prostate http://dx.doi.org/10.1002/pros.22491.

  6. Ripert, T. et al. Six years' experience with high-intensity focused ultrasonography for prostate cancer: oncological outcomes using the new 'Stuttgart' definition for biochemical failure. BJU Int. 107, 1899–1905 (2011).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Guillonneau, B. New treatments for localized tumours—what matters first?. Nat Rev Urol 9, 414–415 (2012). https://doi.org/10.1038/nrurol.2012.133

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrurol.2012.133

Search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer