Alzheimer disease (AD) biomarkers reflect specific features of AD pathology. These biomarkers may be used in the diagnosis and staging of AD, or may act as surrogate end points in clinical trials. Thus, a thorough understanding of the diagnostic accuracy of and longitudinal change in cerebrospinal fluid and MRI AD biomarkers is important.
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Prins, N., van Swieten, J. MRI and CSF biomarkers in AD—accuracy and temporal change. Nat Rev Neurol 6, 650–651 (2010). https://doi.org/10.1038/nrneurol.2010.173
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DOI: https://doi.org/10.1038/nrneurol.2010.173