Multiple interventions can retard the progression or prevent the development of microvascular and macrovascular complications in patients with diabetes, but the effects of early glycaemic control seem to be longer lasting than those of blood pressure control. Cherney et al. now report that renin–angiotensin system blockade has sustained beneficial effects in patients with type 1 diabetes mellitus.
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The work of the authors is supported by the European Union (HEALTH-2011-278249-EU-MASCARA).
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J. Menne has received lecture fees from the following companies: Berlin Chemie, Daiichi Sankyo, Novartis. C. Chatzikyrkou declares no competing interests.
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Chatzikyrkou, C., Menne, J. Legacy effects of RAS blockade in diabetes mellitus. Nat Rev Nephrol 9, 566–568 (2013). https://doi.org/10.1038/nrneph.2013.173
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DOI: https://doi.org/10.1038/nrneph.2013.173
