Faecal microbiota transplantation (FMT) has a role in treating recurrent Clostridium difficile infection; however, practical concerns regarding modes of administration have limited its widespread use. Youngster and colleagues investigated the safety and efficacy of frozen FMT capsules (from prescreened unrelated donors) for the treatment of recurrent C. difficile infection in 20 patients. No serious adverse events were noted, and 18 of 20 patients achieved resolution of diarrhoea. Large studies are needed to confirm these results.