Fibrosis severity and graft loss in liver transplant recipients with hepatitis C are associated with older donor age. In their cohort study, which spanned three eras of donor age policies, Flemming et al. investigated the effect of restricting donor liver age for recipients with hepatitis C (to 30 years versus 48 years for recipients without hepatitis C). Donor age restriction had no obvious adverse effect on wait-list time or early post-transplantation survival.
References
Flemming, J. A. et al. Restricting liver transplant recipients to younger donors does not increase wait-list time or drop out rate: the hepatitis C experience. Liver Transpl. 10.1002/lt.23937
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Wait-list time and drop-out rate for patients with hepatitis C is not increased by restricting donor age. Nat Rev Gastroenterol Hepatol 11, 516 (2014). https://doi.org/10.1038/nrgastro.2014.137
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DOI: https://doi.org/10.1038/nrgastro.2014.137
