In this prospective multicentre study, a urinary trypsinogen-2 dipstick test was given to 412 patients presenting to the emergency room or hospitalized with acute abdominal pain. Sensitivity and specificity for acute pancreatitis were 68.6% and 87.1%. Sensitivity for pancreatitis caused by alcohol or gallstones was 72.2% and 81.8%, higher than for amylase testing. By adjusting the cut-off point, the test achieved 92.2% sensitivity and a positive likelihood ratio of 7.63.
ORIGINAL RESEARCH PAPER
Mayumi, T. et al. Validity of urinary trypsinogen-2 test in the diagnosis of acute pancreatitis. Pancreas doi:10.1097/MPA.0b013e3182480ab7
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Most cases of acute pancreatitis can be diagnosed or ruled out by urinary trypsinogen-2 dipstick test. Nat Rev Gastroenterol Hepatol 9, 302 (2012). https://doi.org/10.1038/nrgastro.2012.81
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DOI: https://doi.org/10.1038/nrgastro.2012.81
