Predicting outcome in acute liver failure (ALF) of any kind is difficult and frustrating. To date, no clinical or biochemical combination of markers has proved to be of much value, owing primarily to lack of sensitivity when measured against the actual outcomes observed. Cholongitas et al. investigated four readily available prognostic scores in the setting of acetaminophen-induced ALF.
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Lee, W. Determining prognosis in acute liver failure. Nat Rev Gastroenterol Hepatol 9, 192–194 (2012). https://doi.org/10.1038/nrgastro.2012.34
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DOI: https://doi.org/10.1038/nrgastro.2012.34