In their cross-sectional study, Hurrel, Genta and Dellon examined esophageal biopsy samples that were taken from 2008 to 2010 as part of a large US pathology database. Using a temperate climate (as defined by the Köppen–Geiger climate class) as a reference, the researchers found that esophageal eosinophilia was more likely in a cold climate or an arid climate than in a tropical climate. They believe that geographical and climate patterns can be used to help identify candidate antigens for investigation.
ORIGINAL RESEARCH PAPER
Hurrel, J. M. et al. Prevalence of esophageal eosinophilia varies by climate zone in the United States. Am. J. Gastroenterol. doi:10.1038/ajg.2012.6
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Climate influences esophageal eosinophilia prevalence. Nat Rev Gastroenterol Hepatol 9, 186 (2012). https://doi.org/10.1038/nrgastro.2012.28
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DOI: https://doi.org/10.1038/nrgastro.2012.28