A joint task force of the American Association of Clinical Endocrinologists and the American Thyroid Association has produced updated clinical guidelines for the diagnosis and treatment of hypothyroidism in adults. The new guidelines include 52 evidence-based best practice recommendations to help clinicians provide optimal care for patients with hypothyroidism.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Chakera, A. J., Pearce, S. H. & Vaidya, B. Treatment for primary hypothyroidism: current approaches and future possibilities. Drug Des. Devel. Ther. 6, 1–11 (2012).
Baskin, H. J. et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism. Endocr. Pract. 8, 457–469 (2002).
Garber, J. R. et al. Clinical practice guidelines for hypothyroidism in adults: co-sponsored by American Association of Clinical Endocrinologists and the American Thyroid Association. Endocr. Pract. http://dx.doi.org/10.4158/EP12280.GL.
Grozinsky-Glasberg, S., Fraser, A., Nahshoni, E., Weizman, A. & Leibovici, L. Thyroxine-triiodothyronine combination therapy versus thyroxine monotherapy for clinical hypothyroidism: meta-analysis of randomized controlled trials. J. Clin. Endocrinol. Metab. 91, 2592–2599 (2006).
Panicker V. et al. Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination thyroxine plus triiodothyronine therapy in hypothyroid patients. J. Clin. Endocrinol. Metab. 94, 1623–1629 (2009).
Wiersinga, W. M., Duntas, L., Fadeyev, V., Nygaard, B. & Vanderpump, M. P. 2012 ETA guidelines: the use of L-T4 + L-T3 in the treatment of hypothyroidism. Eur. Thyroid J. 1, 55–71 (2012).
Stagnaro-Green, A. et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid 21, 1081–1125 (2011).
De Groot, L. et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. J. Clin. Endocrinol. Metab. 97, 2543–2565 (2012).
Haddow, J. E. et al. Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. N. Engl. J. Med. 341, 549–555 (1999).
Lazarus, J. H. et al. Antenatal thyroid screening and childhood cognitive function. N. Engl. J. Med. 366, 493–501 (2012).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Vaidya, B. New guidelines for the management of hypothyroidism. Nat Rev Endocrinol 9, 11–12 (2013). https://doi.org/10.1038/nrendo.2012.226
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrendo.2012.226
