Recent patents related to p53

The tumour suppressor p53 — which regulates genes that are involved in DNA repair, metabolism, cell cycle arrest, apoptosis and senescence — is the most frequently mutated gene in human cancer. On p217, Lane et al. highlight the development of drugs and new targets within the p53 pathway, as well as challenges such as targeting protein–protein interactions and a fragile mutant transcription factor. Here in Table 1 we highlight selected patent applications published in the past year related to p53. Data were researched using the Espacenet database.

Table 1 Published patent applications related to p53