Glycine transporters have a vital role in the regulation of levels of glycine, which acts as an inhibitory neurotransmitter and a modulator of neuronal excitation levels. As Harvey and Yee discuss in their Review on p866, targeting glycine transporters could rebalance glycine homeostasis in schizophrenia, pain and alcohol dependence. They highlight recent advances in the biology of glycine reuptake and transport as well as the development of compounds that block glycine transporters
Here in Table 1 we highlight patent applications published in the past 2 years. Data were researched using the Espacenet database.
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Harrison, C. Patents related to glycine transporters. Nat Rev Drug Discov 12, 821 (2013). https://doi.org/10.1038/nrd4171
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DOI: https://doi.org/10.1038/nrd4171