Using triple-negative breast tumours established in mice, Verbrugge et al. have examined whether the effects of radiotherapy can be enhanced when used in combination with monoclonal antibodies that boost the immune system (α-CD137 and α-CD40) or that inhibit immunosuppression (α-PD1). nT cells.
ORIGINAL RESEARCH PAPER
Verbrugge, I. et al. Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies. Cancer Res. doi:10.1158/0008-5472.CAN-12-0210
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Radiotherapy and immunotherapy, perfect match. Nat Rev Clin Oncol 9, 429 (2012). https://doi.org/10.1038/nrclinonc.2012.118
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DOI: https://doi.org/10.1038/nrclinonc.2012.118
