A recent study analyzed the timing of non-platinum chemotherapy in combination with radiotherapy in patients with head-and-neck cancer and showed that only those who had not undergone surgery benefited from the chemoradiation therapy. However, inconsistencies between some results of this study and those of previous studies, along with the advent of novel, less toxic combinations of radiotherapy, are likely to limit the development of the chemotherapy regimens used in their study.
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J. Bernier is a consultant for the following companies: Imclone, Merck-Serono, Sanofi-Aventis. L. Licitra declares no competing interests.
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Bernier, J., Licitra, L. Chemoradiation in head-and-neck cancer—are we any closer?. Nat Rev Clin Oncol 7, 247–249 (2010). https://doi.org/10.1038/nrclinonc.2010.50
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DOI: https://doi.org/10.1038/nrclinonc.2010.50
