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Chemotherapy

Current drugs still have potential in advanced ovarian cancer

Nature Reviews Clinical Oncology volume 7, pages 191–193 (2010)Cite this article

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Dose-dense administration of paclitaxel as well as intraperitoneal administration of platinum and paclitaxel as first-line treatments provide similar advantages compared with standard treatment in advanced ovarian cancer. Both approaches, however, need to be confirmed by additional studies. A low dose of pegylated liposomal doxorubicin combined with carboplatin is superior to standard paclitaxel and carboplatin in relapsed platinum-sensitive ovarian cancer.

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Figure 1: Comparison of a | PFS and b | overall survival curves from the JGOG study on dose-dense therapy and the GOG study on IP therapy.1,2

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  1. Department of Cancer Epidemiology and South Swedish Regional Tumour Registry, Lund University and Lund University Hospital, SE-221 85, Lund, Sweden

    Thomas Hogberg

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  1. Thomas Hogberg
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Hogberg, T. Current drugs still have potential in advanced ovarian cancer. Nat Rev Clin Oncol 7, 191–193 (2010). https://doi.org/10.1038/nrclinonc.2010.37

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