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Neutral not a loss: phosphoinositides beyond the head group

Nature Methods volume 8, pages 219–220 (2011)Cite this article

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Detection of cellular PtdIns(3,4,5)P3 by combination of chemical derivatization and tandem mass spectroscopy has been demonstrated.

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Figure 1: Enhanced detection of Ptdlns(3,4,5)P3 by methylation and subsequent tanden mass spectroscopy.

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Authors and Affiliations

  1. Department of Biomedicine, Matthias P. Wymann is at the Institute of Biochemistry and Genetics, University of Basel, Basel, Switzerland.,

    Matthias P Wymann

  2. Markus R. Wenk is in the Department of Biochemistry and Department of Biological Sciences, National University of Singapore, Singapore, and the Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland.,

    Markus R Wenk

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  1. Matthias P Wymann
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  2. Markus R Wenk
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Correspondence to Matthias P Wymann or Markus R Wenk.

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Wymann, M., Wenk, M. Neutral not a loss: phosphoinositides beyond the head group. Nat Methods 8, 219–220 (2011). https://doi.org/10.1038/nmeth0311-219

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