By coupling protein cross-linking with reversible affinity purification of cross-linked fragments, a newly reported tool should enable many applications in structural and systems biology.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Tan, D. et al. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. eLife http://dx.doi.org/10.7554/eLife.12509 (2016).
Rights and permissions
About this article
Cite this article
de Souza, N. A multi-purpose cross-linker. Nat Methods 13, 392–393 (2016). https://doi.org/10.1038/nmeth.3860
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.3860
